Nyoteni combines advanced exosome technology with GHK-Cu, a copper peptide associated with supporting healthy skin function, collagen support, and skin renewal pathways. The transdermal formulation is designed to help key ingredients reach beyond the skin surface.

Exosomes are signaling components involved in cellular communication, while GHK-Cu is known for supporting skin repair pathways. With consistent use, consumers typically look for improvements in the appearance of skin texture, firmness, hydration, and overall skin quality.

Nyoteni is formulated as a topical skincare product designed for skin application. Users should follow directions, consider patch testing if they have sensitive skin, and consult a healthcare professional for specific skin concerns.

No. Our cream formulation is intended to complement your existing daily skin routine. It is intended to be applied at night to help skin cell regeneration while at sleep. It also can be used in combination with exosome facial therapy post treatment to enhance results. It can also be used or applied as standalone treatment.

No. For skin care topical use they are regarded as a safe mechanism to help regenerate damaged tissue and skin cells. They aren’t cells, so you don’t run the risk of rejection. Exosomes have the advantages of low immunogenicity.

The formulation is designed for daily application at night. The amount applied depends on each individual’s skin condition.

With daily use the 30 gram container should last 60-90 days.

Results can vary as well as the timeliness in which they can be noticed. Some individuals experience a noticeable difference in as little as few weeks while others in 3-6 months. We encourage daily use and weekly documented monitoring to help assess your progress.

No. Exosomes are “acellular” meaning they are not cells. They are micro vesicles that carry a “payload” of rich proteins, lipids, and nucleic acids that carry immense benefits for cell/tissue regeneration.

Our formula is designed to help exosomes penetrate skin layers to be effective in transporting rich proteins / lipids / nucleic acids etc. However it can be used alongside micro-needling to enhance results. We encourage careful handling/application or medical guidance.

Our formulation efficacy depends on each user’s condition. The length of positive results can vary. To maintain a minimum constant threshold of acquired results as well as continued improvement we recommend using our cream 2-3 times during the year when each 30 gram bottle is finished.

 Yes. We believe in having the “purest” and “least manipulated” exosomes which is the foundation of the success of our formula. With this in mind we also screen for and do not accept any exosome tissue deriving from any type of COVID 19 vaccinated donors.

Our cream is an elegant based formulation in that it is important for it to contain properties that allows carriage or transportation of exosomes. It is a night cream and not a “light” cream, we have formulated it to be “not so heavy” but also “not so light” as it is important for exosomes to have the right conduit and environment to be effective in its’ time lapse of daily skin application, hence the night time interval preference. We recommend lighter amounts of cream application or halt usage completely should you experience severe discomfort or redness. Consult with your dermatologist if you have a severe skin condition before usage.

Our cream formulation contains a proprietary environment for which our unique exosome isolation process becomes complimentary to the well being of exosomes to be effective and maintain viability. However, there is a time limit as the “activeness” of our exosomes decrease over time. This is why the concentration of exosomes has to be at high thresholds (trillions) in order to still maintain effectiveness and duration. Based on several clinical tests over a year before product launch it has been determined an active effective date threshold of 90 days.

There are no “wonder” creams that can give you results in few days. However, we have seen with many tests and trials through leading regenerative clinical specialists over the last year some exciting results that have changed so many lives. We are also involved in exploring through further clinical testing other more complex topical conditions that are starting to show positive results with the use of our cream formulation. We hope to soon open our clinical and research forum for all.

We have our reviews section here on our website as well as our Instagram page (@nyoteni.ex) for those that wish to tell their stories as we are excited to create a community to help each other prosper in our goals towards a healthy looking skin.

Yes. Maintaining the cream refrigerated is always welcomed and can only extend viability. However, it has been formulated to last 90 days at room temperature. If you live in warm weather climate refrigeration may be recommended.

Please email us at info@nyoteni.com and our team will respond to your questions. For order related questions please email us at orders@nyoteni.com

We produce orders in small batches in order to maintain freshness and a meticulous quality assurance protocol. So we always ask a little patience for orders to be shipped. We usually fill orders in 1-3 business days.

Yes. We have grown from the b2b clinical context and are currently providing many clinical establishments our cream for providers to give to their patients for take home use after in-situ exosome therapy.

A prescription is not needed for application of our cream formulation.

Yes. Our cream formulation was borne with the idea of helping individuals experience a boost and increase results in conjunction with their therapy sessions. It is the perfect approach.

We are expanding and always welcome distributorship/collaboration opportunities. Please visit our Collaboration Section and fill out your information with and a representative will contact you.

Yes. We are an FDA registered Tissue Bank Facility and process Wharton’s Jelly mesenchymal stem cells and lyophilized exosomes for cosmetic and regenerative applications. This is our foundation. Send us an email at info@nyoteni.com for more information and a representative will contact you.

Our exosome based formula is highly effective within most part at the 90 day threshold. Past 90 days there is a probability that the active payloads on exosomes decrease in viability as they become “permanently dormant”. This is why the importance of establishing a once-a-day night time application habit is highly recommended. Your cream is carefully made as your order is received guaranteeing an effective high viability rate. The 30 gram bottle is designed to last 60-90 of daily usage depending on your skin condition.